Phytoestrogens, plant produced hormones, are marketed to alleviate menopausal symptoms because studies indicate increased incidence of breast cancer in women undergoing estrogen Hormone Replacement Therapy. We studied the potential proliferative effects of phytoestrogens on the breast cancer cell line T47D-KBluc. HPLC isolated components of black cohosh, red clover, and grape seed extracts were assessed for proliferative effects using the MTT assay. Our results suggest that grape seed demonstrated the greatest proliferative effects.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Manning, Taylor Margaret

Contributors

• White, Abbie

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-050114-115917

Advisor

• Buckholt, Michael Allan
• Rulfs, Jill

Year

• 2014

Date created

• 2014-05-01

Resource type

• Major Qualifying Project

Major

• Biology & Biotechnology

Rights statement

• In Copyright