The objective of this study was to use functional Magnetic Resonance Imaging to investigate the brain activity of nicotine-addicted rats when the stimulus was introduced during the refractory period. The results confirmed that regions of the brain normally activated by nicotine are relatively inactive during the refractory period. These results coupled with other studies of drug reaction can be used in the development of pharmaceuticals aimed at specific regions of the brain or at determining targeted drug delivery schedules.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Dolatshahi Zand, Amid
• Angjeli, Endri

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-042408-112010

Advisor

• Sullivan, John M.

Year

• 2008

Date created

• 2008-04-24

Location

• New York

Resource type

• Major Qualifying Project

Major

• Biomedical Engineering

Rights statement

• In Copyright

Last modified

• 2020-12-31