Student Work
Library MosSCI: A New Approach to Multiplexed Transgenic Strain Generation
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open in viewerEarly embryogenesis cell fate specification in Caenorhabditis elegans is driven primarily by post-transcriptional regulation, in which RNA-binding proteins bind to the 3' UTRs of complementary mRNAs. POS-1 is a RNA-binding protein necessary for germline specification in early embryogenesis. Transgenic worm strains with possible POS-1 binding sites were used to study the underlying mechanisms of stem cell fate regulation by POS-1. We also modified the Mos1-mediated single-copy insertion method to increase production efficiency of transgenic strains of C. elegans.
- This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
- Creator
- Colaboradores
- Publisher
- Identifier
- E-project-042911-150135
- Advisor
- Year
- 2011
- Sponsor
- Date created
- 2011-04-29
- Resource type
- Major
- Rights statement
- Última modificação
- 2023-11-03
Relações
- Em Collection:
Itens
Permanent link to this page: https://digital.wpi.edu/show/8w32r7104