Bisphenol A (BPA), a component of plastics, triggers formation of stress granules (SGs). The pathway of BPA-induced SG formation is unknown. It was hypothesized that BPA activates the G protein coupled estrogen receptor GPER1. Use of an agonist (G1) and antagonist (CIMBA) suggest that GPER1 plays a role in BPA-induced SGs. An epidemiologic study examined the relationship between female reproductive cancers (FRCs) and socioeconomic status as a marker of BPA exposure. A linear relationship was observed in NY state.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Hutchinson, Hope

Subject

• Community
• Health
• Well-Being

Publisher

• Worcester Polytechnic Institute

Identifier

• 105891
• E-project-042723-103014

Advisor

• Farny, Natalie
• Faber, Brenton

Year

• 2023

Date created

• 2023-04-27

Resource type

• Major Qualifying Project

Major

• Biology & Biotechnology

Source

• E-project-042723-103014

Rights statement

• In Copyright

Last modified

• 2023-06-21