Student Work
THE EFFECT OF A PUTATIVE CHROMATIN-OPENING ELEMENT ON METHOTREXATE AMPLIFICATION
PúblicoPrevious work at Abbott Bioresearch Center on a putative chromatin-opening sequence inserted into a plasmid dubbed "genomic vector", suggested that the vector caused an increase in the rate of methotrexate-induced amplification in Chinese Hamster Ovary cells. This project supported the hypothesis that the genomic sequence may cause an increase in amplification effects; however, the increase was not statistically significant, nor was the increase in expression of antibody in CHO cells when compared to the parental vector.
- This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
- Creator
- Colaboradores
- Publisher
- Identifier
- E-project-122007-173047
- Advisor
- Year
- 2007
- Sponsor
- Date created
- 2007-12-20
- Resource type
- Major
- Rights statement
Las relaciones
- En Collection:
Elementos
Elementos
Miniatura | Título | Visibilidad | Embargo Release Date | Acciones |
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JoBrosiusMQP_Final.pdf | Público | Descargar |
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