Interstitial Cystitis is a debilitating bladder disease of young and middle-aged women. Knowledge of its etiology and pathogenesis is limited. Our research used the EAC (Experimental Autoimmune Cystitis) rat model developed by Dr. Judith Luber-Narod to investigate the hypothesis that the disease is autoimmune in nature. Bladder tissue from control and EAC rats was compared at the light and electron microscopy levels, where morphological differences were found, along with evidence of increased autoimmune sensitivity in EAC rats.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Anderson, Leigh Heather
• Rasku, Julie Anna
• Boyd, Katie Taylor

Publisher

• Worcester Polytechnic Institute

Identifier

• 99D101M

Advisor

• Gibson, Daniel G.

Year

• 1999

Date created

• 1999-01-01

Resource type

• Major Qualifying Project

Major

• Biology & Biotechnology

Rights statement

• In Copyright