Cell size control is required to maintain cells within a viable size range making it an essential cellular process. Cell-cycle regulatory proteins, such as Cdc13 and Cdc25, are expressed at cell size-dependent concentrations. This study extended observations of expressions of Cdc25 by developing a comparison model that demonstrates the accumulation of a control protein, GFP, which expresses time-dependency behavior. This will allow the exploration of the mechanisms of time-dependent expression and determine that Cdc25 is in fact a size-dependent protein.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Guerrero Negron, Lauren

Publisher

• Worcester Polytechnic Institute

Identifier

• 65736
• E-project-042822-153500

Keyword

• Fission Yeast
• S. pombe
• Cdc25
• Cell Size Regulation

Advisor

• Heilman, Destin

Year

• 2022

Sponsor

• UMass Medical School

Date created

• 2022-04-28

Resource type

• Major Qualifying Project

Major

• Biochemistry

Rights statement

• In Copyright