Myocardial infarction can lead to heart failure resulting in the need for cardiac transplant. To limit the need for a transplant, a suturable cardiac scaffold was designed to be placed on the infarct site. The patch utilizes a decellularized spinach leaf with silicone suture patches and arterial tubing. Tests for strength, biocompatibility, and arterial connection were completed. The data showed that the scaffold has potential to be surgically implantable and encourages further research to be performed to determine its effect on functional recovery of myocardial tissue.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Guyette, Connor E.
• Swan, Karistan D.
• Berthiaume, Jacqueline M.
• Rath, Nicholas S.

Publisher

• Worcester Polytechnic Institute

Identifier

• 22381
• E-project-050521-180716

关键词

• cardiac patch
• myocardial infarction
• decellularized spinach leaf

Advisor

• Gaudette, Glenn R.

Year

• 2021

Date created

• 2021-05-05

Resource type

• Major Qualifying Project

Major

• Biomedical Engineering

Rights statement

• In Copyright