Student Work

 

Skeletal Muscle Tissue Engineering System to Mimic In Vivo Development Public

Downloadable Content

open in viewer

Skeletal muscle atrophy can occur for a number of reasons including degenerative diseases and age-related sarcopenia. Current pre-clinical studies for regeneration therapies are solely reliant on animal models, which do not accurately mimic human tissue and chemistry. The purpose of developing this device was to provide a reproducible manner of creating an in vitro skeletal muscle model that will aid in preclinical therapy testing. The device was designed to maintain a sterile environment for tissue culture, which provides anchorage, periodic strain, and generates an electric field to stimulate contraction. The intended output of the device is the controlled culture of a minimal functional unit of skeletal muscle that surpasses current standards of in vitro and in vivo pre-clinical models.

Creator
Publisher
Identifier
  • E-project-042413-115942
Advisor
Year
  • 2013
Date created
  • 2013-04-24
Resource type
Major
Rights statement
License

Relationships

In Collection:

Items

Permanent link to this page: https://digital.wpi.edu/show/6682x527t