Student Work

Building a Bacterial Biosensor for the Detection of Synthetic Opioids

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Fentanyl is a synthetic opioid, 50 to 100 times more potent than heroin and morphine. Many biosensors used for the detection of narcotics today are expensive and limited. To detect fentanyl in aqueous samples, we designed a fentanyl-responsive genetic circuit in E. coli. The efficiency and sustainability of genetic circuit induction under low nutrient conditions was tested. The fentanyl biosensor allows traces of drugs to be detected within community water sources allowing monitoring of narcotics use.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
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  • E-project-051720-182614
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  • 2020
Date created
  • 2020-05-17
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