Student Work

Caenorhabditis elegans: The Search for srf-6 Mutations

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Parasitic nematodes may evade host immune systems by changing surface composition during infection. C. elegans is a free-living nematode with a conserved development and cuticle structure utilized as a parasitic model. srf-6 mutant worms fail to make surface antigen switches that occur facultatively in the wild type. The whole genome sequences of three srf-6 mutants were determined to identify the DNA sequence corresponding to srf-6. This project’s objective was to find and confirm srf-6 mutations in the genome sequence by re-sequencing the candidate gene in mutant DNA.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
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  • E-project-050114-163547
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Year
  • 2014
Date created
  • 2014-05-01
Location
  • Worcester
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