The bacteriocidal effect of metal ions on microbes has been well known for many years. The growth kinetics of bacterial cultures are also known to be strongly influenced by the presence of quorum sensing compounds. In this study we look at the effect of metal ions in combination with culture medium in which bacteria have been grown, the conditioned medium will contain quorum sensing compounds. The organism we study is Staphylococcus aureus (S. aureus). S. aureus produces a quorum sensing molecule called autoinducing peptide (AIP). As a first step to looking at this mechanism we have looked at the toxicity of copper and silver ions in the presence of conditioned media.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Watson, Jared D

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-060118-154619

Advisor

• Lambert, Christopher R.

Year

• 2018

Date created

• 2018-06-01

Resource type

• Major Qualifying Project

Major

• Chemistry

Rights statement

• In Copyright