Student Work
Upconversion Nanoparticles For Photodynamic Therapy
公开可下载的内容
open in viewerThe goal of this project was to establish a noninvasive cancer therapy with minimal side effects, low cost, and specific in targeting tumor cells. The team engineered novel and biocompatible Upconversion Nanoparticles (UCNPs) with a calcium fluoride shell Ytterbium and Erbium core conjugated with a photoactive prodrug 5-Aminolevulinic Acid (ALA-UCNP). UCNPs converted near-infrared light into visible light when excited at ~980nm. Emission of the red light from the ALA-UCNPs activates ALA, causing cell death with exposure to 980nm laser light.
- This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
- Creator
- 贡献者
- Publisher
- Identifier
- E-project-042214-122140
- Advisor
- Year
- 2014
- Sponsor
- Date created
- 2014-04-22
- Resource type
- Major
- Rights statement
- 最新修改
- 2021-02-02
关系
- 属于 Collection:
项目
Permanent link to this page: https://digital.wpi.edu/show/4m90dw81z