Student Work
Upconversion Nanoparticles For Photodynamic Therapy
PúblicoThe goal of this project was to establish a noninvasive cancer therapy with minimal side effects, low cost, and specific in targeting tumor cells. The team engineered novel and biocompatible Upconversion Nanoparticles (UCNPs) with a calcium fluoride shell Ytterbium and Erbium core conjugated with a photoactive prodrug 5-Aminolevulinic Acid (ALA-UCNP). UCNPs converted near-infrared light into visible light when excited at ~980nm. Emission of the red light from the ALA-UCNPs activates ALA, causing cell death with exposure to 980nm laser light.
- This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
- Creator
- Colaboradores
- Publisher
- Identifier
- E-project-042214-122140
- Advisor
- Year
- 2014
- Sponsor
- Date created
- 2014-04-22
- Resource type
- Major
- Rights statement
- Última modificação
- 2021-02-02
Relações
- Em Collection:
Itens
Itens
Miniatura | Título | Acesso | Embargo Release Date | Ações |
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|
FinalMQP-UCNP-Report_2014.pdf | Público | Baixar |
Permanent link to this page: https://digital.wpi.edu/show/4m90dw81z