Induced potassium transport in the human erythrocyte was investigated. It is shown that transport induced by volume increase is chloride dependent. Furosemide experimentation confirms the effects of volume regulation are due to a cotransport mechanism. Propranolol studies confirm an additive effect when combined with volume change, revealing no interference. Activation by propranolol involves a phosphatase, thus rendering its activation effect similar to volume regulated activation. Charybdotoxin and TMO studies determine that propranolol only activates the co-transport mechanism.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Woodcock, Matthew Jon
• Yergen, Cara M.

Publisher

• Worcester Polytechnic Institute

Identifier

• 99D040M

Advisor

• Hobey, William D.

Year

• 1999

Date created

• 1999-01-01

Resource type

• Major Qualifying Project

Major

• Biochemistry

Rights statement

• In Copyright