Parasitic nematodes infect billions of humans and cost billions in crop damage. Their success may be due in part to surface protein alterations as the worm develops. Yet surface antigen expression on a molecular level is poorly understood. Using C. elegans as a model nematode, anti-peptide antibodies directed against peptide sequences derived from putative C. elegans surface protein genes were obtained. This project aims to better understand antigenic surface molecule expression using Western blotting. Antigenic surface proteins of mixed stage worms range from 35-52kDa.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Mutetwa, Batsirai Tafadzwa

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-042507-133229

Advisor

• Politz, Samuel M.

Year

• 2007

Date created

• 2007-04-25

Resource type

• Major Qualifying Project

Major

• Biochemistry

Rights statement

• In Copyright

Last modified

• 2021-02-01