Student Work

Taxus plant suspension cultures can be used to produce paclitaxel, an anticancer compound. Currently PTX is administered systemically, which can have severe side effects. To minimize these effects, this project investigates the use of a plant cell culture (PCC) delivery system for paclitaxel through exploring retention of paclitaxel and other specialized metabolites through PCC processing, optimization of drug delivery through various polymers, predicted release in an in vitro breast cancer model, and consideration of the pharmacokinetics of the optimized system.

Last modified

• 11/20/2020

Creator

• Thurlow, Summer L.
• Johnson, Michaela Faith
• Rivers, Jason B.

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-051620-041057

Advisor

• Coburn, Jeannine M
• Roberts, Susan Celia

Year

• 2020

Date created

• 2020-05-16

Resource type

• Major Qualifying Project

Major

• Chemical Engineering

Rights statement

• In Copyright

License

• All rights reserved

Relationships

In Collection:

• Major Qualifying Projects

Items

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	Paclitaxel_Release_System.pdf	2020-08-22	Public	Press to Select an action Download