Ice Nucleation Detection in RBC Samples during Supercooling
Pubblico DepositedThis project aims to develop a device and associated protocol to monitor supercooled red blood cell samples and detect when ice nucleation occurs. This device would minimize samples lost to current invasive testing methods for nucleation. A typical sample consists of a sedimented red blood cell layer, a supernatant layer, and a layer of mineral oil. When nucleation occurs, cells lyse and release hemoglobin; this causes the supernatant layer of the sample to change from a clear to a red color, which can be detected using a photometer. This photometer runs continuously with a vibration sensor and temperature sensor in order to monitor storage conditions. Through various testing methods, this device design was determined to be successful in detecting ice nucleation.
- This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
- Creator
- Subject
- Publisher
- Identifier
- 105626
- E-project-042623-211731
- Parola chiave
- Advisor
- Year
- 2023
- Sponsor
- UN Sustainable Development Goals
- Date created
- 2023-04-26
- Resource type
- Major
- Source
- E-project-042623-211731
- Rights statement
- Ultima modifica
- 2024-04-08
Relazioni
- In Collection:
Articoli
Permanent link to this page: https://digital.wpi.edu/show/0k225f58m