Computer Vision Analysis of in Vitro Biological Neural Network Connectivity

Fongeallaz, Connor; Pylypenko, Taras

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Computer Vision Analysis of in Vitro Biological Neural Network Connectivity

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In the emerging field of biological neural networks (BNNs), little is known about the effect of external stimulus on cell connectivity. In this paper, we explore how different methods for culturing n2a mouse neuroblasts affect the morphology of the resulting BNN. We also improve upon existing methods of computer image analysis to identify the boundaries and connectivity of the cells. In the future, this technology could be used to track the changes in the connectivity of the BNN when exposed to external stimuli

This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

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