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Ependymin Immunoreactivity in Limulus polyphemus Public

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Ependymin is a neurotrophic factor found during certain cellular events related to neuronal development, cellular regeneration, and memory consolidation. Since its discovery in goldfish in 1976, ependymin has been partially sequenced and shows notable conservation through many different species. This allowed for the development of an 8 aa antibody against ependymin which can be used to identify the protein's presence in various tissues. Using immunohistological techniques we have attempted to determine the location of ependymin in several stages of Limulus development. Our preliminary fluorescent staining of whole-mount crabs indicates a strong presence of ependymin throughout the central nervous system in the 1st, 3rd and 4th juvenile instar stages.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
  • E-project-043009-083039
  • 2009
Date created
  • 2009-04-30
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