The Journal of Cell Culture Models, Volume 1

Roberts, Louis A.

Generic Work

The Journal of Cell Culture Models, Volume 1

Public Deposited

Collection Description: While often cells are represented and pictured as discrete biological units, we aim to expand our vision where cells are more realistically considered as building blocks of tissues. By focusing on their interactions with other cell types and biocompatible materials, we can better model the integrated nature and three-dimensional structures that inform cell survival, proliferation, differentiation, and biological function. This approach better allows us to understand the molecular and cellular processes that mediate and affect scarring, wound healing, drug toxicity, and cell development. How do cells choose between these outcomes, and how can different cell types and their interactions with materials direct these processes? Our biologically authentic cell culture models help answer these research questions with the goal of contributing to regenerative medicine applications. This collection can be viewed as a “Journal of Cell Culture Models”, and contains articles written following the processes and adhering to the conventions of the primary scientific literature. Each work herein was authored by undergraduate students at Worcester Polytechnic Institute (WPI) enrolled in an authentic research laboratory course, and credits the teaching assistant and instructor (as corresponding author). Generating and disseminating this collection was made possible via the generous support of the WPI Women’s Impact Network (WIN) EmpOwER program.

Foreword for Volume I: This inaugural volume reflects the contributions of the students enrolled in the undergraduate laboratory course BB 3570 Cell Culture Models for Tissue Regeneration at Worcester Polytechnic Institute. The students choose, design, build, and test their models. Subsequently, the students prepare their findings as an open-access journal article. While the research and writing are guided by the instructor and teaching assistant, the students are the scientists conceiving, executing, and disseminating their work. I hope they are as proud of their work as I am!

Volume I, 2023 contributors: Olivia Atkins, Claire Behning, Alexander Boucher, Cleo Caldwell, Katherine Corbin, Lilah Delbou, Binh Diec, John Gabelmann, Kelly Heffernan, Lia Kelly, Samantha Lopez, Grace McCarthy, Jaya Mills, Emma Smith, Yizhe Ma (teaching assistant), Louis Roberts (instructor).

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