Index Catalog // Digital WPI

Propensity of Endogenous Alternative Splicing to Mediate Mutative Damage

Keyword:: Mutation, Alternative Splicing, Cancer, mRNAseq, Statistics, and Machine Learning
Creator:: Lutz, Ashley
Advisor:: Korkin, Dmitry
Publisher:: Worcester Polytechnic Institute
Date Created:: 2019-04-25
Resource Type:: Thesis
Degree:: MS
Unit (Department):: Bioinformatics & Computational Biology

Mathematical Modeling and Experimental Approaches Reveal Novel Roles of Cortical Dynein in Spindle Dynamics and Centrosome Clustering

Keyword:: Mitotic Spindle, Model, Mitosis, and Centrosome
Creator:: Mercadante, Dayna
Advisor:: Manning, Amity L. and Olson, Sarah D
Publisher:: Worcester Polytechnic Institute
Date Created:: 2022-05-31
Resource Type:: Dissertation
Degree:: PhD
Unit (Department):: Bioinformatics & Computational Biology

Histone H4 lysine 20 methyltransferase SUV4-20H2 regulates mitotic fidelity

Keyword:: Chromatin, Aurora B, Methyltransferase, Mitosis, Histone Posttranslational Modification, and Centromere
Creator:: Hahn, Sabine
Advisor:: Manning, Amity L.
Publisher:: Worcester Polytechnic Institute
Date Created:: 2023-11-08
Resource Type:: Dissertation
Degree:: PhD
Unit (Department):: Biology & Biotechnology

Defining the mechanisms contributing to genomic instability following RB loss

Keyword:: Mitosis, Aurora B kinase, and Genomic Instability
Creator:: Crowley, Elizabeth
Advisor:: Manning, Amity L.
Publisher:: Worcester Polytechnic Institute
Date Created:: 2022-12-06
Resource Type:: Dissertation
Degree:: PhD
Unit (Department):: Biology & Biotechnology

The Role of Gαq-Mediated Stress Granules in Neuron Function

Creator:: Jackson, Lela
Advisor:: Scarlata, Suzanne Frances
Publisher:: Worcester Polytechnic Institute
Date Created:: 2022-06-18
Resource Type:: Dissertation
Degree:: PhD
Unit (Department):: Chemistry & Biochemistry

Functionalized Aptamers for Lead (Pb (II)) Biosensing and Therapeutic Applications

Keyword:: Heavy metals, Aptamers, Lead biosensing, Lead, Lead aptamers, and Therapeutic for acute lead poisoning
Creator:: Ramis de Ayreflor Reyes, Solimar
Advisor:: Farny, Natalie
Publisher:: Worcester Polytechnic Institute
Date Created:: 2022-04-27
Resource Type:: Dissertation
Degree:: MS
Unit (Department):: Biology & Biotechnology

Heterochromatin HIstone Methylation Regulates Genome Stability

Creator:: Herlihy, Conor P.
Advisor:: Manning, Amity L.
Publisher:: Worcester Polytechnic Institute
Date Created:: 2021-01-15
Resource Type:: Dissertation
Degree:: PhD
Unit (Department):: Biology & Biotechnology

Elucidating a Conserved Myosin XI-RabE GTPase Interaction that is Required for Polarized Cell Growth in Plants

Keyword:: Rab GTPases, RNA Interference, Polarized Growth, Vesicle Trafficking, Structure-guided Mutagenesis, and Myosin XI
Creator:: Orr, Robert G.
Advisor:: Vidali, Luis
Publisher:: Worcester Polytechnic Institute
Date Created:: 2020-08-13
Resource Type:: Dissertation
Degree:: PhD
Unit (Department):: Biology & Biotechnology

Studying inter- and intra-tumor heterogeneity of triple-negative breast cancer

Keyword:: unsupervised learning, clustering, TNBC, and cancer
Creator:: Leshchyk, Anastasia
Advisor:: Korkin, Dmitry
Publisher:: Worcester Polytechnic Institute
Date Created:: 2019-04-28
Resource Type:: Thesis
Degree:: MS
Unit (Department):: Bioinformatics & Computational Biology

Elucidating Mechanisms of Replication-associated Synthetic lethality with RB loss and PARP inhibition

Keyword:: DNA damage, RB1, Retinoblastoma, PARP, Replication, and Epigenetics
Creator:: Gutierrez Zamalloa, Luis
Advisor:: Manning, Amity L.
Publisher:: Worcester Polytechnic Institute
Date Created:: 2022-11-01
Resource Type:: Dissertation
Degree:: PhD
Unit (Department):: Biology & Biotechnology

Elucidating the Function of Myosin XI in Polarized Cell Growth and Investigating the Chitin-induced Calcium-mediated Immune Response in P. patens.

Creator:: Galotto, Giulia
Advisor:: Vidali, Luis
Publisher:: Worcester Polytechnic Institute
Date Created:: 2020-11-07
Resource Type:: Dissertation
Degree:: PhD
Unit (Department):: Biology & Biotechnology

Should I stay or should I go? The fight or flight defense responses in Taxus cell culture

Creator:: McKee, Michelle C
Advisor:: Roberts, Susan Celia
Publisher:: Worcester Polytechnic Institute
Date Created:: 2020-08-02
Resource Type:: Dissertation
Degree:: PhD
Unit (Department):: Biology & Biotechnology

Leveraging Omics Data to Expand the Value and Understanding of Alternative Splicing

Keyword:: Omics and Alternative Splicing
Creator:: Johnson, Nathan T.
Advisor:: Korkin, Dmitry
Publisher:: Worcester Polytechnic Institute
Date Created:: 2019-04-08
Resource Type:: Dissertation
Degree:: PhD
Unit (Department):: Bioinformatics & Computational Biology

Fibroblast activation and pro-fibrotic phenotypes: modulation by FGF2 and MAPK signaling

Keyword:: myofibroblast, MAPK, fibrosis, FGF2, and fibroblast
Creator:: Dolivo, David
Advisor:: Dominko, Tanja
Publisher:: Worcester Polytechnic Institute
Date Created:: 2018-04-19
Resource Type:: Dissertation
Degree:: PhD
Unit (Department):: Biology & Biotechnology

School of Arts and Sciences Newsletter, Fall 2023

Keyword:: newsletter
Creator:: WPI School of Arts and Sciences
Publisher:: Worcester Polytechnic Institute
Date Created:: 2023
Resource Type:: Other

Regulation of Genome Stability during mitosis

Creator:: Shell, Hannah
Advisor:: Manning, Amity L.
Publisher:: Worcester Polytechnic Institute
Date Created:: 2023-04-27
Resource Type:: Major Qualifying Project

Proximity Labeling Identifies Cell Cycle Specific Interactions of Retinoblastoma Protein

Keyword:: Retinoblastoma Protein, Ribosome, Cancer, Splicing, Glycosylation, and Proximity Labeling
Creator:: Rashkovskii, Mikhail
Advisor:: Manning, Amity L. and Argüello, José M.
Publisher:: Worcester Polytechnic Institute
Date Created:: 2023-05-03
Resource Type:: Major Qualifying Project

Green Labs: assessing and Reducing Laboratory waste at WPI

Keyword:: Sustainability, Green Labs, and Lab Waste
Creator:: Denmark, Bryce, Noons, Noelle, McDonough, Jake, Soofi, Anjum, and Mackisey, Dylan
Advisor:: Manning, Amity L. and Mathisen, Paul P.
Publisher:: Worcester Polytechnic Institute
Date Created:: 2023-03-03
Resource Type:: Interactive Qualifying Project

Modeling Multipolar Cell Division through Forces Generated by Microtubules Interacting with Motors and Kinetochores

Keyword:: mathematical modeling, microtubule, centrosome movement, rotational force, chromokinesin and kinetochore, and chromosome
Creator:: Chen, Ye
Advisor:: Olson, Sarah D
Publisher:: Worcester Polytechnic Institute
Date Created:: 2023-03-07
Resource Type:: Major Qualifying Project

WPI Journal : the magazine of Worcester Polytechnic Institute, Volume 118, Issue 3, Fall 2022

Keyword:: campus publication, magazine, and alumni
Creator:: Worcester Polytechnic Institute
Publisher:: Worcester Polytechnic Institute
Date Created:: 2022
Resource Type:: Journal

WPI Journal : the magazine of Worcester Polytechnic Institute, Volume 117, Issue 1, Spring 2021

Keyword:: campus publications, alumni, and magazine
Creator:: Worcester Polytechnic Institute
Publisher:: Worcester Polytechnic Institute
Date Created:: 2021
Resource Type:: Journal

A Rhetorical Inquiry: Molecular Characterization of the Histone Methyltransferase Suv420 as a Grant Proposal

Keyword:: Genre System, Grant Proposals, Grant Writing, Suv420, Histone methyltransferases, and Casein Kinase 2
Creator:: Nunez, Cristian
Advisor:: Manning, Amity L. and Madan, Ryan Smith
Publisher:: Worcester Polytechnic Institute
Date Created:: 2022-04-28
Resource Type:: Major Qualifying Project

Regulation of Aneuploidy

Creator:: Maroju, Jagruthi
Advisor:: Manning, Amity L.
Publisher:: Worcester Polytechnic Institute
Date Created:: 2022-04-28
Resource Type:: Major Qualifying Project

Metaphase Chromosome Alignment is Sensitive to Dynein-Dependent Forces at the Cell Cortex

Keyword:: Mitosis, Chromosome Segregation, Kinetochores, Chromosome Alignment, Cell Biology, and Microtubules
Creator:: Belanger, Kylie
Advisor:: Manning, Amity L.
Publisher:: Worcester Polytechnic Institute
Date Created:: 2022-03-18
Resource Type:: Major Qualifying Project

WPI Journal : the magazine of Worcester Polytechnic Institute, Volume 114, Issue 1, Spring 2018

Keyword:: campus publications, alumni, and magazine
Creator:: Worcester Polytechnic Institute
Publisher:: Worcester Polytechnic Institute
Date Created:: 2018
Resource Type:: Journal

WPI Journal : the alumni magazine of Worcester Polytechnic Institute, Volume 12, Issue 1, Fall 2015

Keyword:: campus publications, magazine, and alumni
Creator:: Worcester Polytechnic Institute
Publisher:: Worcester Polytechnic Institute
Date Created:: 2015
Resource Type:: Journal

In Silico Edgetic Profiling and Network Analysis of Human Genetic Variants, with an Application to Disease Module Detection

Keyword:: Next Generation Sequencing
Creator:: Cui, Hongzhu
Advisor:: Korkin, Dmitry
Publisher:: Worcester Polytechnic Institute
Date Created:: 2020-05-18
Resource Type:: Dissertation
Degree:: PhD
Unit (Department):: Bioinformatics & Computational Biology

Transcriptional Regulation of Non-Coding RNAs by Retinoblastoma Tumor Suppressor Protein

Creator:: Sadiq, Hammad M.
Advisor:: Manning, Amity L.
Publisher:: Worcester Polytechnic Institute
Date Created:: 2019-04-25
Resource Type:: Major Qualifying Project
Award:: Provost's MQP Award

Mutations in Kinesin 5A effect on Mitochondrial Mobility in Amyotrophic Lateral Sclerosis and Hereditary Spastic Paraplegia

Creator:: Garcia, Jacqueline Pilar
Advisor:: Manning, Amity L.
Publisher:: Worcester Polytechnic Institute
Date Created:: 2019-04-25
Resource Type:: Major Qualifying Project

Tracking DNA Damage Repair in Cancerous Cells

Creator:: Nicolella, Alyssa Alexandra and Corace, Michael L.
Advisor:: Manning, Amity L. and Korkin, Dmitry
Publisher:: Worcester Polytechnic Institute
Date Created:: 2020-05-18
Resource Type:: Major Qualifying Project

Defining Cell Cycle-Specific Interactions of the pRB Tumor Suppressor

Creator:: Stadnicki, Emily Jane
Advisor:: Manning, Amity L. and Heilman, Destin
Publisher:: Worcester Polytechnic Institute
Date Created:: 2020-05-14
Resource Type:: Major Qualifying Project

Investigating the Role of MycN and p53 Binding in Pediatric Neuroblastoma

Creator:: Honzel, Brooke E.
Advisor:: Manning, Amity L.
Publisher:: Worcester Polytechnic Institute
Date Created:: 2020-05-13
Resource Type:: Major Qualifying Project

Predicting DNA Damage in Fluorescent Imaging

Creator:: McDonough, Daniel and Vadivazhagu, Surya
Advisor:: Manning, Amity L. and Korkin, Dmitry
Publisher:: Worcester Polytechnic Institute
Date Created:: 2020-05-06
Resource Type:: Major Qualifying Project

Nicholas Nickleby

Creator:: Dickens, Charles and Browne, Hablot Knight
Publisher:: Chapman and Hall
Date Created:: 1838-1839
Resource Type:: Book

Centriole Amplification Independently from Aurora A Overexpression Causes Resistance to Alisertib Treatment

Creator:: Navarro Serer, Bernat
Advisor:: Manning, Amity L. and Heilman, Destin
Publisher:: Worcester Polytechnic Institute
Date Created:: 2017-04-26
Resource Type:: Major Qualifying Project

Determining the Role and Implications of Aurora A Kinase Inhibition In Acute Myeloid Leukemia

Creator:: Childers, Eva Peng
Advisor:: Manning, Amity L.
Publisher:: Worcester Polytechnic Institute
Date Created:: 2017-03-23
Resource Type:: Major Qualifying Project

Regulation of Mitotic DNA Damage by the Retinoblastoma Tumor Suppressor Protein

Creator:: Gurska, Lindsay Meg
Advisor:: Manning, Amity L.
Publisher:: Worcester Polytechnic Institute
Date Created:: 2017-04-25
Resource Type:: Major Qualifying Project

Perinatal database.

Keyword:: Application software--Development and Medical care
Creator:: Ram, Prashanth, Phu, David Q., and Ngo, Brandon
Advisor:: Strong, Diane M.
Publisher:: Worcester Polytechnic Institute
Date Created:: 1999-01-01
Resource Type:: Interactive Qualifying Project

Gene fusions in cancer: Classification of fusion events and regulation patterns of fusion pathway neighbors

Keyword:: Cancer, semi-supervised machine learning, gene fusion, Machine Learning, and chromosomal abnormalities
Creator:: Hughes, Katelyn
Advisor:: Korkin, Dmitry
Publisher:: Worcester Polytechnic Institute
Date Created:: 2016-05-05
Resource Type:: Thesis
Degree:: MS
Unit (Department):: Bioinformatics & Computational Biology

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