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Regulating Valvular Interstitial Cell Phenotype by Boundary Stiffness

Stichwort:

myofibroblast, valvular interstitiat cells, residual tension, TGF-β, 3, stiffness, cell-generated force, tension reduction, Heart valves, fibrin gel, and contraction

Schöpfer:

Kural, Mehmet Hamdi

Advisor:

Billiar, Kristen

Herausgeber:

Worcester Polytechnic Institute

Datum erstellt:

2014-06-01

Resource Type:

Dissertation

Degree:

PhD

Unit (Department):

Biomedical Engineering
A Comparative Analysis of the Biomechanics and Biochemistry of Cell-Derived and Cell-Remodeled Matrices: Implications for Wound Healing and Regenerative Medicine

Stichwort:

strength, fibrin gel, glycosaminoglycans, tissue growth, Regenerative medicine, wound-healing model, tissue formation, human, proteoglycans, biomechanical characterization, UTS, biochemical characterization, fibroblast-populated, growth factors, cell-derived matrix, mechanics, Fibroblasts, collagen, serum-free, extensibility, total protein content, tension, chemically-defined medium, thickness, cell-remodeled matrix, tissue regeneration, collagen gel, and failure strain

Schöpfer:

Ahlfors, Jan-Eric Wilhelm

Advisor:

Billiar, Kristen

Herausgeber:

Worcester Polytechnic Institute

Datum erstellt:

2004-05-03

Resource Type:

Thesis

Degree:

MS

Unit (Department):

Biomedical Engineering