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Dominko, Tanja
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Histone H4 lysine 20 methyltransferase SUV4-20H2 regulates mitotic fidelity
Keyword:
Chromatin
,
Aurora B
,
Methyltransferase
,
Mitosis
,
Histone Posttranslational Modification
, and
Centromere
Creator:
Hahn, Sabine
Advisor:
Manning, Amity L.
Publisher:
Worcester Polytechnic Institute
Date Created:
2023-11-08
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biology & Biotechnology
From Farm to Lab: The Potential of Decellularized Plant Leaves for Sustainable Meat Production
Keyword:
Skeletal Muscle
,
Cultured Meat
,
Decellularization
,
Cellular Agriculture
, and
Lab-grown Meat
Creator:
Jones, Jordan
Advisor:
Gaudette, Glenn
and
Dominko, Tanja
Publisher:
Worcester Polytechnic Institute
Date Created:
2023-12-13
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Elucidating Mechanisms of Replication-associated Synthetic lethality with RB loss and PARP inhibition
Keyword:
DNA damage
,
RB1
,
Retinoblastoma
,
PARP
,
Replication
, and
Epigenetics
Creator:
Gutierrez Zamalloa, Luis
Advisor:
Manning, Amity L.
Publisher:
Worcester Polytechnic Institute
Date Created:
2022-11-01
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biology & Biotechnology
Creating a Functional Cardiac Patch From Decellularized Spinach Leaves
Keyword:
iPS-CM
,
decellularized plant
,
tissue engineering
, and
cardiac tissue patch
Creator:
Robbins, Emily
Advisor:
Gaudette, Glenn R.
Publisher:
Worcester Polytechnic Institute
Date Created:
2021-08-06
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Tuning the Biophysical and Biochemical Cues of Fibrin Microthread Scaffolds Towards the Treatment of Volumetric Muscle Loss
Keyword:
tissue engineering
,
fibrin
,
skeletal muscle regeneration
,
biomaterials
,
volumetric muscle loss
, and
microthreads
Creator:
Carnes, Meagan E.
Advisor:
Pins, George D
Publisher:
Worcester Polytechnic Institute
Date Created:
2020-09-29
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Bringing together engineering and entrepreneurship: understanding the role of tethered C-CHY1 in the fight against antimicrobial resistance
Keyword:
Business Model Canvas
,
Entrepreneurship
,
QCM-D
,
Antimicrobial peptides
,
Quartz-crystal microbalance with dissipation
, and
Chrysophsin-1
Creator:
Alexander, Todd E
Advisor:
Camesano, Terri Anne
Publisher:
Worcester Polytechnic Institute
Date Created:
2019-08-06
Resource Type:
Dissertation
Degree:
PhD
Engineering silk fibroin scaffolds to model hypoxia in neuroblastoma
Keyword:
Hypoxia
,
Silk Fibroin
,
Neuroblastoma
, and
Scaffold
Creator:
Ornell, Kimberly J
Advisor:
Coburn, Jeannine M
Publisher:
Worcester Polytechnic Institute
Date Created:
2019-08-07
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Cell-Derived Extracellular Matrix Scaffolds Developed using Macromolecular Crowding
Keyword:
macromolecular crowding
,
cell-derived matrices
,
Hyaluronic Acid
, and
extracellular matrix
Creator:
Shendi, Dalia M
Advisor:
Rolle, Marsha Whitney
Publisher:
Worcester Polytechnic Institute
Date Created:
2019-08-07
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Optimization of spheroid formation: the case of Mn9D cells as a novel tool to assess cytotoxicity and neurodegeneration
Creator:
Ippolito, Amanda Nicole
,
Digioia, Andrea Michelle
,
Atwater, Britney Lee
, and
DiFelice, Lauren Ashley
Advisor:
Rolle, Marsha Whitney
Publisher:
Worcester Polytechnic Institute
Date Created:
2013-01-14
Resource Type:
Major Qualifying Project
Wound Healing Effects of a Modified Collagen-Binding Antimicrobial Peptide LL37
Creator:
Dion, Megan Ashley
Advisor:
Camesano, Terri Anne
Publisher:
Worcester Polytechnic Institute
Date Created:
2015-12-18
Resource Type:
Major Qualifying Project
Design and Study of Collagen-Tethered LL37 for Chronic Wound Healing
Keyword:
Quartz crystal microbalance with dissipation
,
chronic wounds
,
LL-37
,
Antimicrobial peptides
,
mechanism
,
wound healing
,
cCBD-LL37
,
collagen binding domain
,
fCBD-LL37
,
tether
, and
collagen
Creator:
Lozeau, Lindsay Dawn
Advisor:
Camesano, Terri Anne
Publisher:
Worcester Polytechnic Institute
Date Created:
2018-01-23
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Chemical Engineering
Characterization of arginine methyltransferase PRMT8 in cells with increased plasticity
Keyword:
cancer biology
,
reprogramming
,
senesence
,
proliferation
, and
arginine methylation
Creator:
Hernandez, Sarah
Advisor:
Dominko, Tanja
Publisher:
Worcester Polytechnic Institute
Date Created:
2016-01-17
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biology & Biotechnology
Electrically Conducting Biofibers: Approaches to Overcome the Major Challenges in the Clinical Translation of a Tissue Engineered Cardiac Patch
Keyword:
decellularization
,
plant scaffold
,
clinical translation
, and
cardiac tissue engineering
Creator:
Gershlak, Joshua R
Advisor:
Gaudette, Glenn R.
Publisher:
Worcester Polytechnic Institute
Date Created:
2018-08-30
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Oxygen-mediated basic fibroblast growth factor (FGF2) effects on adult human dermal fibroblasts
Keyword:
developmental plasticity
,
basic fibroblast growth factor
,
hypoxia-inducible factor
,
human fibroblasts
, and
low oxygen
Creator:
Kashpur, Olga
Advisor:
Dominko, Tanja
Publisher:
Worcester Polytechnic Institute
Date Created:
2015-05-08
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biology & Biotechnology
Fibroblast activation and pro-fibrotic phenotypes: modulation by FGF2 and MAPK signaling
Keyword:
myofibroblast
,
MAPK
,
fibrosis
,
FGF2
, and
fibroblast
Creator:
Dolivo, David
Advisor:
Dominko, Tanja
Publisher:
Worcester Polytechnic Institute
Date Created:
2018-04-19
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biology & Biotechnology
Designing Fibrin Microthread Scaffolds for Skeletal Muscle Regeneration
Keyword:
Regenerative medicine
,
Biomaterials
,
Tissue Engineering
,
skeletal muscle regeneration
,
Stem cells
,
microthreads
,
myoblasts
,
volumetric muscle loss
,
ECM proteins
,
Fibrin
, and
hepatocyte growth factor
Creator:
Grasman, Jonathan M
Advisor:
Pins, George D
Publisher:
Worcester Polytechnic Institute
Date Created:
2015-01-09
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Kekkon6 and Kekkon3 - Novel Insights into the Kekkon Family
Keyword:
Kekkon Family
,
LIGs
, and
Tricellular Junctions
Creator:
Arata, Michelle Denise
Advisor:
Duffy, Joseph B.
Publisher:
Worcester Polytechnic Institute
Date Created:
2011-04-27
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biology & Biotechnology
A mechanism for the FGF2-mediated down-regulation of integrin alpha-11 identified through studying altered adhesome of human dermal fibroblasts undergoing early Mesenchymal-to-Epithelial Transition
Keyword:
FGF2
,
ECM
,
hESC
, and
ITGA11
Creator:
Grella, Alexandra R
Advisor:
Dominko, Tanja
Publisher:
Worcester Polytechnic Institute
Date Created:
2015-01-29
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biology & Biotechnology
Engineering the Keratinocyte Microenvironment: Harnessing Topography to Direct Cellular Function
Keyword:
dermal–epidermal junction
,
keratinocyte function
,
microtopography
, and
tissue engineered skin
Creator:
Clement, Amanda Lynn
Advisor:
Pins, George D
Publisher:
Worcester Polytechnic Institute
Date Created:
2015-01-12
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Role of Fibroblast Growth Factor 2 in Maintenance of Multipotency in Human Dermal Fibroblasts Treated with Xenopus Laevis Egg Extract Fractions
Keyword:
Cellular reprogramming
,
FGF2
,
Xenopus laevis egg extract
,
Stem cells
,
Pluripotency
, and
Induced pluripotent stem cells
Creator:
Kole, Denis
Advisor:
Dominko, Tanja
Publisher:
Worcester Polytechnic Institute
Date Created:
2014-04-28
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biology & Biotechnology
Engineered Vascular Tissue Generated by Cellular Self-Assembly
Keyword:
Self-Assembly
,
cell-derived
, and
vascular graft
Creator:
Gwyther, Tracy A
Advisor:
Rolle, Marsha Whitney
Publisher:
Worcester Polytechnic Institute
Date Created:
2012-01-13
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Mechanical Activation Of Valvular Interstitial Cell Phenotype
Keyword:
stretch
,
VICs
,
stiffness
,
myofibroblast
, and
transforming growth factor beta
Creator:
Quinlan, Angela
Advisor:
Billiar, Kristen
Publisher:
Worcester Polytechnic Institute
Date Created:
2012-08-20
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Identifying the Molecular Mechanism of Indole-3-Acetic Acid Detection in the Fungi Saccharomyces cerevisiae and Candida albicans
Keyword:
S. cerevisiae
,
C. albicans
,
IAA
, and
Indole-3-acetic acid
Creator:
Perelta, Alisha Nicole
Advisor:
Rao, Reeta Prusty
Publisher:
Worcester Polytechnic Institute
Date Created:
2012-05-03
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biology & Biotechnology
Conditioning of Mesenchymal Stem Cells Initiates Cardiogenic Differentiation and Increases Function in Infarcted Hearts
Keyword:
cardiomyoplasty
,
cardiac mechanical function
,
stem cell differentiation
, and
Mesenchymal Stem Cells
Creator:
Guyette, Jacques Paul
Advisor:
Gaudette, Glenn R.
Publisher:
Worcester Polytechnic Institute
Date Created:
2012-01-16
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
A dissection of Kekkon5 and its role in mediating epithelial junction architecture
Keyword:
LRR
,
Immunoglobulin domain
,
Armadillo
,
Cellular adhesion
, and
Kekkon5
Creator:
Ernst, Christina Lynn
Advisor:
Duffy, Joseph B.
Publisher:
Worcester Polytechnic Institute
Date Created:
2010-04-28
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biology & Biotechnology
Award:
Provost's MQP Award
Modification of Surfaces for Biological Applications
Keyword:
biological applications
and
Surface Modification
Creator:
Milkani, Eftim
Advisor:
McGimpsey, W. Grant
Publisher:
Worcester Polytechnic Institute
Date Created:
2010-04-29
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Chemistry & Biochemistry
Designing Bioengineered Skin Substitutes Containing Microfabricated Basal Lamina Analogs to Enhance Skin Regeneration
Keyword:
fibronectin
,
bioengineered skin substitutes
,
microenvironment
, and
keratinocytes
Creator:
Bush, Katie Ann
Advisor:
Pins, George D
Publisher:
Worcester Polytechnic Institute
Date Created:
2009-01-29
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
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6
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