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Filtering by: Advisor Flaherty, Patrick J. Contributor Albrecht, Dirk Unit (Department) Biomedical Engineering

RVD2: An ultra-sensitive variant detection model for low-depth heterogeneous next-generation sequencing data

Keyword:

variant detection; Bayesian statistics; graphical

Creator:

He, Yuting

Advisor:

Flaherty, Patrick J.

Publisher:

Worcester Polytechnic Institute

Date Created:

2014-04-29

Resource Type:

Thesis

Degree:

MS

Unit (Department):

Biomedical Engineering
Statistical Methods for Characterizing Genomic Heterogeneity in Mixed Samples

Keyword:

Variational inference, Matrix factorization, Next-generation sequencing, Global optimization, Bayesian statistics, and Rare variant detection

Creator:

Zhang, Fan

Advisor:

Flaherty, Patrick J.

Publisher:

Worcester Polytechnic Institute

Date Created:

2016-12-12

Resource Type:

Dissertation

Degree:

PhD

Unit (Department):

Biomedical Engineering