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Lowering Bone Stress Injury Risk by Understanding Loading Angle, Bone Strength, and Training Load
Keyword:
strained volume
,
bone stress injuries
,
loading angle
,
bone strength
,
cumulative loading
, and
finite element modeling
Creator:
Young, Bryhannah
Advisor:
Troy, Karen
Publisher:
Worcester Polytechnic Institute
Date Created:
2023-11-30
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Microfluidic High-Throughput Methods for the Induction and Characterization of Repeatable, Titratable Traumatic Neural Injury in the Nematode Caenorhabditis elegans
Keyword:
Neural Imaging
,
TRPV4
,
C. elegans
,
Traumatic Brain Injury
, and
Microfluidics
Creator:
White, Hamilton
Advisor:
Albrecht, Dirk
Publisher:
Worcester Polytechnic Institute
Date Created:
2023-12-08
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
From Farm to Lab: The Potential of Decellularized Plant Leaves for Sustainable Meat Production
Keyword:
Skeletal Muscle
,
Cultured Meat
,
Decellularization
,
Cellular Agriculture
, and
Lab-grown Meat
Creator:
Jones, Jordan
Advisor:
Gaudette, Glenn
and
Dominko, Tanja
Publisher:
Worcester Polytechnic Institute
Date Created:
2023-12-13
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Development of a Transparent Peptide Functionalized Bacterial Derived Cellulose Wound Dressing
Keyword:
Cellulose
,
Transparency
,
Antimicrobial Peptides
,
Cellulose Binding Peptides
,
Biomaterials
, and
Wound Dressing
Creator:
van Zyl, Elizabeth
Advisor:
Coburn, Jeannine M
Publisher:
Worcester Polytechnic Institute
Date Created:
2023-08-03
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Engineered blood vessels with spatially distinct regions for disease modeling
Keyword:
smooth muscle
,
bioreactor
,
microsphere
,
tissue engineered blood vessel
, and
disease modeling
Creator:
Strobel, Hannah A.
Advisor:
Rolle, Marsha Whitney
Publisher:
Worcester Polytechnic Institute
Date Created:
2018-04-24
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Streamlining Tissue Engineering Workflows: Comparing Tissue Formation Between Freshly Cultured and Directly Thawed Cells
Keyword:
Cells
,
Rings
,
Viability
,
Freshly Thawed
,
Tissue model
, and
Tissue Engineering
Creator:
Santos-Heiman, Timothy
Advisor:
Rolle, Marsha Whitney
Publisher:
Worcester Polytechnic Institute
Date Created:
2023-04-26
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
INVESTIGATING THE ROLE OF APOPTOSIS IN CALCIFICATION OF THE AORTIC VALVULAR INTERSTITIAL CELLS
Creator:
Jebeli, Mahvash
Advisor:
Billiar, Kristen
Publisher:
Worcester Polytechnic Institute
Date Created:
2022-12-15
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Applications of Deep Learning in Brain Injury Biomechanics and Spine Image Registration
Keyword:
Spine Image Registration
,
Image-guided Surgery
,
Concussion
,
Deep Learning
, and
Brain Injury
Creator:
Wu, Shaoju
Advisor:
Ji, Songbai
Publisher:
Worcester Polytechnic Institute
Date Created:
2022-08-03
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Ultrasound Computed Tomography for Imaging Tissue-Engineered Blood Vessel
Keyword:
Tissue-Engineered Blood Vessel
,
Ultrasound Computer Tomography Imaging
,
Imaging Techniques in Tissue Engineering
, and
Imaging Tissue Engineering
Creator:
Jaupi, Enxhi
Advisor:
Zhang, Haichong
Publisher:
Worcester Polytechnic Institute
Date Created:
2022-04-27
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
A Cell Spheroid Model of Calcific Aortic Valve Disease: The Role of Apoptosis and Oxidative Stress
Creator:
Coutts, Colin
Advisor:
Billiar, Kristen
Publisher:
Worcester Polytechnic Institute
Date Created:
2021-05-21
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Characterization and Functionalization of Lyophilized Silk Scaffolds for Use in 3D In Vitro Disease Modeling
Keyword:
Biomaterials
,
Kidney Cancer
,
Tissue Engineering
, and
Liver Disease
Creator:
Abbott, Alycia
Advisor:
Coburn, Jeannine M
Publisher:
Worcester Polytechnic Institute
Date Created:
2021-07-16
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Creating a Functional Cardiac Patch From Decellularized Spinach Leaves
Keyword:
iPS-CM
,
decellularized plant
,
tissue engineering
, and
cardiac tissue patch
Creator:
Robbins, Emily
Advisor:
Gaudette, Glenn R.
Publisher:
Worcester Polytechnic Institute
Date Created:
2021-08-06
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Applications of Machine Learning in Real-time Brain Tissue Strain Estimation
Keyword:
Concussion
,
Brain Injury
,
Convolutional Neural Network
,
Deep Learning
, and
Finite Element
Creator:
Ghazi, Kianoosh
Advisor:
Ji, Songbai
Publisher:
Worcester Polytechnic Institute
Date Created:
2021-08-10
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Generation and Dissemination of a Mesenchymal Stem Cell-Derived Functional Smooth Muscle Tissue
Keyword:
disease model
,
tissue engineering
,
mesenchymal stem cells
,
cryopreservation
, and
smooth muscle cells
Creator:
Grosha, Jonian
Advisor:
Rolle, Marsha Whitney
Publisher:
Worcester Polytechnic Institute
Date Created:
2021-08-22
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Decellularized Tobacco Hairy Roots as Novel Tissue Culture Platform
Keyword:
scaffold
,
plant cells
,
decellularization
,
biomaterial
,
cell culture
, and
tobacco hairy roots
Creator:
Rahman, Mohammed Masrur
Advisor:
Coburn, Jeannine M
Publisher:
Worcester Polytechnic Institute
Date Created:
2021-03-11
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Effects of Exoskeleton Walking Therapy in the Distal Femur and Proximal Tibia in Individuals with Chronic Spinal Cord Injury
Keyword:
Biomechanics
,
Bone adaptation
, and
Exoskeleton
Creator:
Mattson, Nicole E.
Advisor:
Troy, Karen
Publisher:
Worcester Polytechnic Institute
Date Created:
2021-04-29
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Advanced Imaging in Neuro-Interventional Surgery
Creator:
King, Robert M.
Advisor:
Billiar, Kristen
and
Gounis, Matthew
Publisher:
Worcester Polytechnic Institute
Date Created:
2021-05-06
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Mechanical Regulation of Cell Death
Creator:
Goldblatt, Zachary
Advisor:
Billiar, Kristen
Publisher:
Worcester Polytechnic Institute
Date Created:
2020-11-02
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Progress Towards a Higher Throughput Uniaxial Stretch Platform with Tunable Stiffness for Mechanobiology Experiments
Creator:
Sutter, Leo B.
Advisor:
Billiar, Kristen
Publisher:
Worcester Polytechnic Institute
Date Created:
2020-08-10
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Defining the Multiscale Relationship between Subject-Specific Bone Strain and Structural Adaptation in the Distal Radius of Women
Keyword:
Quantitative Computed Tomography (QCT)
,
Finite Element (FE)
,
High Resolution Peripheral Quantitative Computed Tomography (HRpQCT)
,
Distal Radius
,
Exercise
, and
Bone Adaptation
Creator:
Mancuso, Megan E
Advisor:
Troy, Karen
Publisher:
Worcester Polytechnic Institute
Date Created:
2020-08-07
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Tuning the Biophysical and Biochemical Cues of Fibrin Microthread Scaffolds Towards the Treatment of Volumetric Muscle Loss
Keyword:
tissue engineering
,
fibrin
,
skeletal muscle regeneration
,
biomaterials
,
volumetric muscle loss
, and
microthreads
Creator:
Carnes, Meagan E.
Advisor:
Pins, George D
Publisher:
Worcester Polytechnic Institute
Date Created:
2020-09-29
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Deep Transfer Learning Applied to Time-series Classification for Predicting Heart Failure Worsening Using Electrocardiography
Keyword:
Heart failure
,
Heart failure worsening prediction
,
Transfer learning
,
Machine Learning
,
Time series analysis
, and
Manifold learning
Creator:
Pan, Xiang
Advisor:
Lee, Kwonmoo
Publisher:
Worcester Polytechnic Institute
Date Created:
2020-04-20
Resource Type:
Dissertation
Degree:
MS
Unit (Department):
Biomedical Engineering
Towards the automatic control of laser ablation for surgical applications
Keyword:
laser dissection pulse
Creator:
Tarabein, Karim A.
Advisor:
Fichera, Loris
Publisher:
Worcester Polytechnic Institute
Date Created:
2019-08-05
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Engineering silk fibroin scaffolds to model hypoxia in neuroblastoma
Keyword:
Hypoxia
,
Silk Fibroin
,
Neuroblastoma
, and
Scaffold
Creator:
Ornell, Kimberly J
Advisor:
Coburn, Jeannine M
Publisher:
Worcester Polytechnic Institute
Date Created:
2019-08-07
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Cell-Derived Extracellular Matrix Scaffolds Developed using Macromolecular Crowding
Keyword:
macromolecular crowding
,
cell-derived matrices
,
Hyaluronic Acid
, and
extracellular matrix
Creator:
Shendi, Dalia M
Advisor:
Rolle, Marsha Whitney
Publisher:
Worcester Polytechnic Institute
Date Created:
2019-08-07
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Effects of PTEN Loss and Activated KRAS Overexpression on Viscoelasticity, Adhesion, and Mechanosensitivity of Breast Epithelial Cells
Keyword:
Cellular Mechanics
,
Atomic Force Microscopy
,
Breast Cancer
,
Cancer Dormancy
,
Triple Negative
, and
Adhesion
Creator:
Linthicum, Will H
Advisor:
Wen, Qi
Publisher:
Worcester Polytechnic Institute
Date Created:
2019-08-08
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Machine Learning Pipelines for Deconvolution of Cellular and Subcellular Heterogeneity from Cell Imaging
Keyword:
Cell Migration
,
Hologram Imaging
,
Machine Learning (Deep Learning)
,
Time Series Analysis
, and
Cell Heterogeneity
Creator:
Wang, Chuangqi
Advisor:
Lee, Kwonmoo
Publisher:
Worcester Polytechnic Institute
Date Created:
2019-08-12
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Portable Bioimpedance System for Early Detection and Prevention of Pressure Injuries
Keyword:
Ulcer
,
Sensor
,
Pressure
,
Bioimpedance
,
Detection
, and
Injury
Creator:
Harvey, Joshua R
Advisor:
Mendelson, Yitzhak
Publisher:
Worcester Polytechnic Institute
Date Created:
2019-09-18
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Micropatterned Fibrin Hydrogels for Increased Cardiomyocyte Alignment
Keyword:
Electrical stimulation
,
hiPS-CM
,
Micropatterning
,
Cardiac tissue engineering
,
Fibrin scaffold
, and
Cardiac patches
Creator:
English, Elizabeth J
Advisor:
Pins, George D
Publisher:
Worcester Polytechnic Institute
Date Created:
2019-12-09
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Development of automated analysis methods for identifying behavioral and neural plasticity in sleep and learning in C. elegans
Keyword:
Associative Learning
,
C. elegans
,
Neural Plasticity
,
Neural Imaging
,
Microfluidics
, and
Sleep
Creator:
Lawler, Daniel E
Advisor:
Albrecht, Dirk
Publisher:
Worcester Polytechnic Institute
Date Created:
2019-12-10
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
RVD2: An ultra-sensitive variant detection model for low-depth heterogeneous next-generation sequencing data
Keyword:
variant detection; Bayesian statistics; graphical
Creator:
He, Yuting
Advisor:
Flaherty, Patrick J.
Publisher:
Worcester Polytechnic Institute
Date Created:
2014-04-29
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Magnetic Resonance Imaging of Neural and Pulmonary Vascular Function
Keyword:
MRI Vascular Stroke Pulmonary Neural
Creator:
Walvick, Ronn P
Advisor:
Helmer, Karl G.
and
Albert, Mitchel
Publisher:
Worcester Polytechnic Institute
Date Created:
2010-08-29
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Evaluation of a Novel Electrospun Polymer Dermal Regeneration Composite Matrix
Keyword:
Biomaterials
,
Electrospinning
, and
dermal regeneration
Creator:
Molignano, Jennifer Elizabeth
Advisor:
Pins, George D
Publisher:
Worcester Polytechnic Institute
Date Created:
2013-12-20
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Designing Modular Fibrin Composite Scaffolds for Enhanced Ventricular Myocardium Regeneration
Keyword:
cardiac patch
and
fibrin composite
Creator:
Chrobak, Megan O'Brien
Advisor:
Pins, George D
Publisher:
Worcester Polytechnic Institute
Date Created:
2017-12-04
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Electrically Conducting Biofibers: Approaches to Overcome the Major Challenges in the Clinical Translation of a Tissue Engineered Cardiac Patch
Keyword:
decellularization
,
plant scaffold
,
clinical translation
, and
cardiac tissue engineering
Creator:
Gershlak, Joshua R
Advisor:
Gaudette, Glenn R.
Publisher:
Worcester Polytechnic Institute
Date Created:
2018-08-30
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Towards the Fabrication of a Fibrin Based Vascular Network
Keyword:
Vascular Engineering
,
Fibrin
, and
Vasculature
Creator:
Santos, Johanna Eleanor
Advisor:
Pins, George D
Publisher:
Worcester Polytechnic Institute
Date Created:
2018-08-16
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Mechanical Regulation of Apoptosis and Calcification within Valvular Interstitial Cells
Keyword:
calcification
,
apoptosis
,
calcific aortic valve disease
,
aortic valvular interstial cells
, and
traction force microscopy
Creator:
Cirka, Heather Ann
Advisor:
Billiar, Kristen
Publisher:
Worcester Polytechnic Institute
Date Created:
2016-04-28
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
An Image-Based Method to Measure Joint Deformity in Inflammatory Arthritis
Keyword:
HRpQCT
,
method
,
non-linear surface transformation
,
CT
,
Imaging
,
inflammatory arthritis
,
MCP
, and
coherent point drift
Creator:
Henchie, Travis F
Advisor:
Troy, Karen
Publisher:
Worcester Polytechnic Institute
Date Created:
2018-04-26
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Automated whole-organism functional screening technologies and neurological disease models in C. elegans
Keyword:
Assay systems
,
C. elegans
,
Neurological disease
,
Biomedical engineering
, and
Neuroscience
Creator:
Lagoy, Ross Charles
Advisor:
Albrecht, Dirk
Publisher:
Worcester Polytechnic Institute
Date Created:
2018-04-26
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Force Feedback for the Patient Side Manipulator of the daVinci Research Kit
Keyword:
daVinci robot
,
PSM
, and
force feedback
Creator:
Novoseltseva, Anna
Advisor:
Fischer, Gregory S.
Publisher:
Worcester Polytechnic Institute
Date Created:
2018-04-25
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
A Machine Learning approach to Febrile Classification
Keyword:
Thermal Imaging
,
Fever Screening
,
Classification
,
Machine Learning
, and
Deep Learning
Creator:
Kostopouls, Theodore P
Advisor:
Lee, Kwonmoo
Publisher:
Worcester Polytechnic Institute
Date Created:
2018-04-25
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Development of a Human Mesenchymal Stem Cell and Pluripotent Stem Cell Derived Cardiomyocyte Seeded Biological Suture for Cell Delivery to Cardiac Tissue for Cardiac Regeneration Applications
Keyword:
fibrin microthreads
,
cardiovascular regeneration
,
Mesenchymal Stem Cells
,
human pluripotent stem cell derived cardiomyocytes
, and
high density mapping
Creator:
Hansen, Katrina J
Advisor:
Gaudette, Glenn R.
Publisher:
Worcester Polytechnic Institute
Date Created:
2017-12-13
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Development of Motion Artifact Rejection Algorithms for Ambulatory Heart Rate and Arterial Oxygen Measurement By A Wearable Pulse Oximeter
Keyword:
Kurtosis
,
Motion Artifacts
,
Adaptive Noise Cancellation
, and
Pulse Oximeters
Creator:
Marwah, Kunal
Advisor:
Mendelson, Yitzhak
Publisher:
Worcester Polytechnic Institute
Date Created:
2012-07-06
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Regulating Valvular Interstitial Cell Phenotype by Boundary Stiffness
Keyword:
myofibroblast
,
valvular interstitiat cells
,
residual tension
,
TGF-β
,
3
,
stiffness
,
cell-generated force
,
tension reduction
,
Heart valves
,
fibrin gel
, and
contraction
Creator:
Kural, Mehmet Hamdi
Advisor:
Billiar, Kristen
Publisher:
Worcester Polytechnic Institute
Date Created:
2014-06-01
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
The Incorporation of Decellularized Cardiac ECM into Fibrin Microthreads
Keyword:
extracellular matrix
,
decellularized
, and
microthreads
Creator:
Marengo, Kaitlyn A
Advisor:
Gaudette, Glenn R.
Publisher:
Worcester Polytechnic Institute
Date Created:
2017-05-26
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
Development of a Biomimetic In Vitro Skeletal Muscle Tissue Model
Keyword:
3D Tissue
,
Tissue Engineering
,
Muscular Dystrophy
,
Skeletal Muscle
,
High-throughput Screening
, and
In Vitro Model
Creator:
Forte, Jason Matthew
Advisor:
Page, Raymond L.
Publisher:
Worcester Polytechnic Institute
Date Created:
2017-04-12
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Designing Fibrin Microthread Scaffolds for Skeletal Muscle Regeneration
Keyword:
Regenerative medicine
,
Biomaterials
,
Tissue Engineering
,
skeletal muscle regeneration
,
Stem cells
,
microthreads
,
myoblasts
,
volumetric muscle loss
,
ECM proteins
,
Fibrin
, and
hepatocyte growth factor
Creator:
Grasman, Jonathan M
Advisor:
Pins, George D
Publisher:
Worcester Polytechnic Institute
Date Created:
2015-01-09
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Statistical Methods for Characterizing Genomic Heterogeneity in Mixed Samples
Keyword:
Variational inference
,
Matrix factorization
,
Next-generation sequencing
,
Global optimization
,
Bayesian statistics
, and
Rare variant detection
Creator:
Zhang, Fan
Advisor:
Flaherty, Patrick J.
Publisher:
Worcester Polytechnic Institute
Date Created:
2016-12-12
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Changes in Passive and Dynamic Mechanical Environments Promote Differentiation to a Contractile Phenotype in Vascular Smooth Muscle Cells
Keyword:
smooth muscle cell
,
3D culture
,
cell-derived matrix
,
Vascular Tissue Engineering
, and
phenotype
Creator:
Reidinger, Amanda Zoe
Advisor:
Rolle, Marsha Whitney
Publisher:
Worcester Polytechnic Institute
Date Created:
2015-04-29
Resource Type:
Dissertation
Degree:
PhD
Unit (Department):
Biomedical Engineering
Multichannel Pulse Oximetry: Effectiveness in Reducing HR and SpO2 error due to Motion Artifacts
Keyword:
Multichannel Pulse Oximetry
,
Pulse Oximetry
,
Motion Artifacts
,
Arterial Oxygen Saturation
,
Multichannel Template-Matching
, and
Heart rate
Creator:
Warren, Kristen Marie
Advisor:
Mendelson, Yitzhak
Publisher:
Worcester Polytechnic Institute
Date Created:
2016-02-02
Resource Type:
Thesis
Degree:
MS
Unit (Department):
Biomedical Engineering
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