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Filtering by: Advisor Manning, Amity L. Collections PhD Dissertations

Histone H4 lysine 20 methyltransferase SUV4-20H2 regulates mitotic fidelity

Keyword:

Chromatin, Aurora B, Methyltransferase, Mitosis, Histone Posttranslational Modification, and Centromere

Creator:

Hahn, Sabine

Advisor:

Manning, Amity L.

Publisher:

Worcester Polytechnic Institute

Date Created:

2023-11-08

Resource Type:

Dissertation

Degree:

PhD

Unit (Department):

Biology & Biotechnology
Elucidating Mechanisms of Replication-associated Synthetic lethality with RB loss and PARP inhibition

Keyword:

DNA damage, RB1, Retinoblastoma, PARP, Replication, and Epigenetics

Creator:

Gutierrez Zamalloa, Luis

Advisor:

Manning, Amity L.

Publisher:

Worcester Polytechnic Institute

Date Created:

2022-11-01

Resource Type:

Dissertation

Degree:

PhD

Unit (Department):

Biology & Biotechnology
Defining the mechanisms contributing to genomic instability following RB loss

Keyword:

Mitosis, Aurora B kinase, and Genomic Instability

Creator:

Crowley, Elizabeth

Advisor:

Manning, Amity L.

Publisher:

Worcester Polytechnic Institute

Date Created:

2022-12-06

Resource Type:

Dissertation

Degree:

PhD

Unit (Department):

Biology & Biotechnology
Mathematical Modeling and Experimental Approaches Reveal Novel Roles of Cortical Dynein in Spindle Dynamics and Centrosome Clustering

Keyword:

Mitotic Spindle, Model, Mitosis, and Centrosome

Creator:

Mercadante, Dayna

Advisor:

Manning, Amity L. and Olson, Sarah D

Publisher:

Worcester Polytechnic Institute

Date Created:

2022-05-31

Resource Type:

Dissertation

Degree:

PhD

Unit (Department):

Bioinformatics & Computational Biology
Heterochromatin HIstone Methylation Regulates Genome Stability

Creator:

Herlihy, Conor P.

Advisor:

Manning, Amity L.

Publisher:

Worcester Polytechnic Institute

Date Created:

2021-01-15

Resource Type:

Dissertation

Degree:

PhD

Unit (Department):

Biology & Biotechnology